Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
| Study Number Sort descending | Lead Group | Study Title | CIRB | Study Status | |
|---|---|---|---|---|---|
| 10647 | ETCTN | Phase I/Ib Study of Eribulin in Combination with ASTX660 (tolinapant) in Metastatic Triple Negative Breast Cancer (TNBC) | Adult CIRB - Early Phase Emphasis | Available to Open | |
| 10655 | ETCTN | Phase I Clinical Trial of CA-4948 (emavusertib) in Combination with FOLFOX Plus Bevacizumab as Frontline Treatment in Patients with Metastatic Colorectal Cancer | Adult CIRB - Early Phase Emphasis | Available to Open | |
| 10657 | ETCTN | Phase I/II Study to Evaluate the Feasibility and Efficacy of Sequential Abemaciclib and Gemcitabine Treatment in Patients with Retinoblastoma (Rb)+ Sarcomas | Adult CIRB - Early Phase Emphasis | Available to Open | |
| 10667 | ETCTN | Pilot Study of Pidnarulex Pharmacodynamics in Patients with Advanced Solid Tumors | Adult CIRB - Early Phase Emphasis | Available to Open | |
| 10670 | ETCTN | A Phase 1 Study of 5-Fluorouracil in Combination with Abemaciclib in Metastatic, Refractory CRC | Adult CIRB - Early Phase Emphasis | Available to Open | |
| 10674 | ETCTN | A Phase I Study Evaluating the Safety of Cirtuvivint as Monotherapy and in Combination with ASTX727 in Patients with Myelodysplastic Syndromes (MDS) and Acute Myeloid Leukemia (AML) | Adult CIRB - Early Phase Emphasis | Available to Open | |
| 10675 | ETCTN | A Randomized Phase 2 Trial of ASTX727 +/- Iadademstat in Accelerated/Blast-Phase Philadelphia Chromosome-Negative Myeloproliferative Neoplasms (MPNs) | Adult CIRB - Early Phase Emphasis | Available to Open | |
| 10699 | ETCTN | A Phase I Trial Combining Triapine with Radiation Therapy for Recurrent Glioblastoma or Astrocytoma | Adult CIRB - Early Phase Emphasis | Available to Open | |
| 10703 | ETCTN | A Phase I/II Trial of Sapanisertib in Combination with Cabozantinib in β-catenin-mutated Hepatocellular Carcinoma (SAPHIRE) | Adult CIRB - Early Phase Emphasis | Available to Open | |
| 10707 | ETCTN | Phase 2 Trial of CBX-12 for Metastatic Chemotherapy-Refractory Microsatellite Stable Colorectal Cancer | Adult CIRB - Early Phase Emphasis | Available to Open |