If you work for – or would like to become – one of our Signatory Institutions, here’s where to get started.

Located on the left navigation bar, you will see a collection of “how-to’s,” which we call Quickguides, that will provide directions on how to begin a particular process, as well as useful tips. Other resources include:


Do you work for an institution that’s part of NCI’s Division of Cancer Prevention Phase 0/I/II Cancer Prevention Clinical Trials Program? These consortia have different processes to gain access to IRBManager and CIRB-approved documents. You’ll want to review the how-to quickguide on navigating the CIRB as a consortia site.