Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
| Study Number Sort descending | Lead Group | Study Title | CIRB | Study Status | |
|---|---|---|---|---|---|
| E1A06 | ECOG | An Intergroup Phase III Randomized Controlled Trial Comparing Melphalan; Prednisone and Thalidomide (MPT) Versus Melphalan; Prednisone and Lenalidomide (Revlimid TM) (MPR) in Newly Diagnosed Multiple Myeloma Patients Who Are Not Candidates for High-Dose Therapy | Adult CIRB - Late Phase Emphasis | Available to Open | |
| E1A11 | ECOG | Randomized Phase III Trial of Bortezomib; LENalidomide and Dexamethasone (VRd) Versus Carfilzomib; Lenalidomide and Dexamethasone (CRd) Followed by Limited or Indefinite DURation Lenalidomide MaintenANCE in Patients with Newly Diagnosed Symptomatic Multiple Myeloma (ENDURANCE) | Adult CIRB - Late Phase Emphasis | Available to Open | |
| E1Q11 | ECOG | EROS: Engendering Reproductive Health within Oncologic Survivorship | Cancer Prevention and Control CIRB | Available to Open | |
| E1Y03 | ECOG | Master Protocol for Pharmacogenetic and Genomic Studies. | Adult CIRB - Late Phase Emphasis | Completed | |
| E2100 | ECOG | A Randomized Phase III Trial of Paclitaxel versus Paclitaxel plus Bevacizumab (rhuMAb VEGF) as First-Line Therapy for Locally Recurrent or Metastatic Breast Cancer | Adult CIRB - Late Phase Emphasis | Completed | |
| E2108 | ECOG | A Randomized Phase III Trial of the Value of Early Local Therapy for the Intact Primary Tumor in Patients with Metastatic Breast Cancer | Adult CIRB - Late Phase Emphasis | Completed | |
| E2112 | ECOG | A Randomized Phase III Trial of Endocrine Therapy plus Entinostat/Placebo in Patients with Hormone Receptor-Positive Advanced Breast Cancer | Adult CIRB - Late Phase Emphasis | Available to Open | |
| E2212 | ECOG | A Randomized; Double-Blinded; Placebo-Controlled Phase II Study of Adjuvant Everolimus Following the Resection of Metastatic Pancreatic Neuroendocrine Tumors to the Liver | Adult CIRB - Early Phase Emphasis | Completed | |
| E2499 | ECOG | Randomized Phase III Trial of Rituximab (NSC #687451) and Autologous Stem Cell Transplantation for B Cell Diffuse Large Cell Lymphoma | Adult CIRB - Late Phase Emphasis | Completed | |
| E2603 | ECOG | A Double-blind; Randomized; Placebo-Controlled Phase III Trial of Carboplatin; Paclitaxel and Sorafenib Versus Carboplatin; Paclitaxel and Placebo in Patients with Unresectable Locally Advanced or Stage IV Melanoma | Adult CIRB - Late Phase Emphasis | Available to Open |