Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
| Study Number Sort descending | Lead Group | Study Title | CIRB | Study Status | |
|---|---|---|---|---|---|
| CALGB-90601 | CALGB | A Randomized Double-Blinded Phase III Study Comparing Gemcitabine; Cisplatin; and Bevacizumab to Gemcitabine; Cisplatin; and Placebo in Patients with Advanced Transitional Cell Carcinoma | Adult CIRB - Late Phase Emphasis | Completed | |
| CALGB-90802 | CALGB | Randomized Phase III Trial Comparing Everolimus Versus Everolimus Plus Bevacizumab for Advanced Renal Cell Carcinoma Progressing After Treatment with Tyrosine Kinase Inhibitors | Adult CIRB - Late Phase Emphasis | Completed | |
| CCTG CE.7 | NCIC CTG | A Phase III Trial of Stereotactic Radiosurgery Compared with Hippocampal-Avoidant Whole Brain Radiotherapy (HA-WBRT) Plus Memantine for 5-15 Brain Metastases | Adult CIRB - Late Phase Emphasis | Available to Open | |
| CCTG MA.39 | NCIC CTG | Tailor RT: A Randomized Trial of Regional Radiotherapy in Biomarker Low Risk Node Positive Breast Cancer | Adult CIRB - Late Phase Emphasis | Available to Open | |
| CCTG-BR38 | CCTG | Consolidative Use of Radiotherapy to Block (CURB2) Oligoprogression in Patients with Metastatic Non-Small-Cell Lung Cancer - A Randomized Phase 3 Trial | Adult CIRB - Late Phase Emphasis | Available to Open | |
| CCTG-CO32 | CCTG | The NEO-RT Trial: A Phase 3 Randomized Trial of Neoadjuvant Chemotherapy, Excision and Observation versus ChemoRadioTherapy for Early Rectal Cancer | Adult CIRB - Late Phase Emphasis | Available to Open | |
| CCTG-HN11 | NCIC CTG | SPECT-CT Guided Elective Contralateral Neck Treatment (Select) for Patients with Lateralized Oropharyngeal Cancer: A Phase III Randomized Controlled Trial | Adult CIRB - Late Phase Emphasis | Available to Open | |
| CCTG-NE1 | CCTG | NET RETREAT: A Phase II Study of 177 Lutetium-DOTATATE Retreatment vs. Everolimus in Metastatic/Unresectable Midgut NET | Adult CIRB - Late Phase Emphasis | Available to Open | |
| CCTG-PR24 | CCTG | Androgen Suppression Combined with Elective Nodal Irradiation and Dose Escalated Prostate Treatment: A Non-Inferiority, Phase III Randomized Controlled Trial of Stereotactic Body Radiation Therapy versus Brachytherapy Boost in Patients with Unfavourable Risk Localized Prostate Cancer (ASCENDE SBRT) | Adult CIRB - Late Phase Emphasis | Available to Open | |
| CCTG-PR26 | CCTG | A Randomized Phase III Clinical Trial for the Addition of Docetaxel to Androgen Receptor Pathway Inhibitors in Patients with Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA Response (TRIPLE-SWITCH) | Adult CIRB - Late Phase Emphasis | Available to Open |