CIRB Studies

Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website

To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.

Review CIRB
Study Status
Study Number Sort descending Lead Group Study Title CIRB Study Status
AREN0534 COG Treatment for Patients with Bilateral; Multicentric; or Bilaterally-Predisposed Unilateral Wilms Tumor: A Groupwide Phase III Study Pediatric CIRB Available to Open
AREN1721 COG A Randomized Phase 2 Trial of Axitinib/Nivolumab Combination Therapy vs. Single Agent Axitinib or Nivolumab for the Treatment of TFE/Translocation Renal Cell Carcinoma (tRCC) Across All Age Groups Pediatric CIRB Available to Open
AREN1921 COG Treatment of Newly Diagnosed Diffuse Anaplastic Wilms Tumors (DAWT) and Relapsed Favorable Histology Wilms Tumors (FHWT) Pediatric CIRB Available to Open
AREN2231 COG Risk Adapted Treatment of Unilateral Favorable Histology Wilms Tumors (FHWT) Pediatric CIRB Available to Open
ARET0231 COG A Single Arm Trial of Systemic and Subtenon Chemotherapy for Groups C and D Intraocular Retinoblastoma Pediatric CIRB Completed
ARET0321 COG A Trial of Intensive Multi-Modality Therapy for Extra-Ocular Retinoblastoma: A Groupwide Phase III Study Pediatric CIRB Available to Open
ARET0331 COG Trial of Systemic Neoadjuvant Chemotherapy for Group B Intraocular Retinoblastoma: A Phase III Limited Institution Study Pediatric CIRB Completed
ARET0332 COG A Study of Unilateral Retinoblastoma With and Without Histopathologic High-Risk Features and the Role of Adjuvant Chemotherapy: A Groupwide Phase III Study Pediatric CIRB Completed
ARET12P1 COG A Multi-institutional Feasibility Study of Intra-Arterial Chemotherapy Given in the Ophthalmic Artery of Children with Retinoblastoma Pediatric CIRB Available to Open
ARET2121 COG Intravitreal Melphalan for Intraocular Retinoblastoma Pediatric CIRB Available to Open