CIRB Studies

Below is the current list of studies covered by the CIRB. Participants should refer to ClinicalTrials.gov for general information about clinical trials. Institutions should refer to the Clinical Trials Support Unit (CTSU) website  for enrollment requirements and accrual status information. 

Study documents approved after July 1, 2013 are available to participating institutions for covered studies on the CTSU website. To request documents approved before July 1, 2013, participating institutions can contact the CIRB Helpdesk.

Review CIRB
Study Number Network Study Title CIRB
9892 ETCTN Phase I Dose-Escalation Bioavailability Study of Oral Triapine in Combination with Concurrent Chemoradiation for Locally Advanced Cervical Cancer (LACC) and Vulvar Cancer Adult CIRB - Early Phase Emphasis
9898 ETCTN A Phase I Trial of AZD9291 and Necitumumab in EGFR-Mutant Non-Small Cell Lung Cancer After Progression on a Previous EGFR Tyrosine Kinase Inhibitor Adult CIRB - Early Phase Emphasis
9899 ETCTN A Phase 1 Trial of the Combination of the Heat Shock Protein-90 (HSP90) inhibitor Onalespib (AT13387) and the Cyclin-Dependent Kinase (CDK) inhibitor AT7519M in patients with Advanced Solid Tumors Adult CIRB - Early Phase Emphasis
9903 ETCTN A Phase 1B Study of AZD9291 in Combination with Navitoclax in EGFR-mutant Non-Small Cell Lung Cancer Following Resistance to Initial EGFR Kinase Inhibitor Adult CIRB - Early Phase Emphasis
9910 ETCTN A phase 1 trial of MLN0128 (TAK-228) in combination with osimertinib (AZD9291) in advanced EGFR mutation positive non-small cell lung cancer (NSCLC) after progression on a previous EGFR tyrosine kinase inhibitor Adult CIRB - Early Phase Emphasis
9914 ETCTN A Phase I Study of a Combination of MM-398 and Veliparib in Solid Tumors Adult CIRB - Early Phase Emphasis
9922 ETCTN A Phase 2 Study of Ibrutinib (PCI-32765) in Refractory Distant Metastatic Cutaneous Melanoma: Correlation of Biomarkers with Response and Resistance Adult CIRB - Early Phase Emphasis
9924 ETCTN A Phase I Trial of the Combination of Lenalidomide and Blinatumomab in Patients with Relapsed or Refractory Non-Hodgkins Lymphoma (NHL) Adult CIRB - Early Phase Emphasis
9925 ETCTN Phase II Trial of Nivolumab for HTLV-Associated Adult T Cell Leukemia/Lymphoma Adult CIRB - Early Phase Emphasis
9930 ETCTN A Phase I Trial of MEDI-570 in Patients with Relapsed/Refractory Peripheral T-Cell Lymphoma (PTCL) Follicular Variant and Angioimmunoblastic T-Cell Lymphoma (AITL) Adult CIRB - Early Phase Emphasis