CIRB Studies

Below is the current list of studies covered by the CIRB. Participants should refer to ClinicalTrials.gov for general information about clinical trials. Institutions should refer to the Clinical Trials Support Unit (CTSU) website  for enrollment requirements and accrual status information. 

Study documents approved after July 1, 2013 are available to participating institutions for covered studies on the CTSU website. To request documents approved before July 1, 2013, participating institutions can contact the CIRB Helpdesk.

Review CIRB
Study Number Network Study Title CIRB
9837 ETCTN Phase I Study of TRC102 in Combination with Cisplatin and Pemetrexed in Patients with Advanced Solid Tumors / Phase II Study of TRC102 with Pemetrexed in Patients Refractory to Pemetrexed and Cisplatin or Carboplatin Adult CIRB - Early Phase Emphasis
9844 ETCTN A Phase 1 Study Evaluating Safety; Tolerability; and Preliminary Antitumor Activity of Entinostat and Nivolumab with or without Ipilimumab in Advanced Solid Tumors Adult CIRB - Early Phase Emphasis
9846 ETCTN Patient-Derived Models Tissue Procurement Protocol For The National Cancer Institute (NCI) Adult CIRB - Early Phase Emphasis
9853 ETCTN A Phase 1 Study of AZD1775 in Combination with Belinostat in Relapsed and Refractory Myeloid Malignancies and Selected Untreated Patients with Acute Myeloid Leukemia Adult CIRB - Early Phase Emphasis
9855 ETCTN A Phase 2 Study of CDX-011 (glembatumumab vedotin) for Metastatic Uveal Melanoma Adult CIRB - Early Phase Emphasis
9874 ETCTN A Phase I Trial of AT13387 in Patients with Locoregionally Advanced Squamous Cell Carcinoma of the Head and Neck (LA-SCCHN) receiving Concurrent Radiation and Cisplatin Adult CIRB - Early Phase Emphasis
9875 ETCTN Phase 2 Study of AT13387 (onalespib) in ALK+ ALCL; MCL; and BCL-6+ DLBCL Adult CIRB - Early Phase Emphasis
9876 ETCTN Phase 1b Study of HSP90 Inhibitor, AT13387 (onalespib) in Combination with Paclitaxel in Patients with Advanced, Triple Negative Breast Cancer. Adult CIRB - Early Phase Emphasis
9878 ETCTN A Phase 1/2 Trial of Erlotinib and Onalespib lactate in EGFR-Mutant Non-Small Cell Lung Cancer Adult CIRB - Early Phase Emphasis
9881 ETCTN A Phase 2 Study of Cediranib in Combination with Olaparib in Advanced Solid Tumors Adult CIRB - Early Phase Emphasis