CIRB Studies

Below is the current list of studies covered by the CIRB. Participants should refer to ClinicalTrials.gov for general information about clinical trials. Institutions should refer to the Clinical Trials Support Unit (CTSU) website  for enrollment requirements and accrual status information. 

Study documents approved after July 1, 2013 are available to participating institutions for covered studies on the CTSU website. To request documents approved before July 1, 2013, participating institutions can contact the CIRB Helpdesk.

Review CIRB
Study Number Network Study Title CIRB
10603 ETCTN A Phase 2 Study of M1774 in Refractory SPOP-mutant Prostate Cancer Adult CIRB - Early Phase Emphasis
10605 ETCTN A Phase 1 Study of ZEN003694 (ZEN-3694) in Combination with Cetuximab and Encorafenib in Patients with Refractory BRAF V600E Metastatic Colorectal Cancer Adult CIRB - Early Phase Emphasis
10608 ETCTN A Phase II Trial of Durvalumab with Gemcitabine and Cisplatin as Neoadjuvant Therapy for High-Risk Resectable Intrahepatic Cholangiocarcinoma Adult CIRB - Early Phase Emphasis
10612 ETCTN A Randomized Phase 2 Study of Daratumumab-Selinexor-Velcade-Dexamethasone (Dara-SVD) for High-Risk Newly Diagnosed Multiple Myeloma Adult CIRB - Early Phase Emphasis
10614 ETCTN A Phase 1/2 Study of Nivolumab and Ipilimumab in Combination with Sirolimus and Prednisone in Kidney Transplant Recipients with Selected Unresectable or Metastatic Cutaneous Cancers Adult CIRB - Early Phase Emphasis
10620 ETCTN A Phase 1b Trial of Teclistamab in Combination with Iberdomide for Relapsed/Refractory Multiple Myeloma Adult CIRB - Early Phase Emphasis
10629 ETCTN A Phase I Dose Finding and Phase II Randomized Trial of Iadademstat Combined with Immune Checkpoint Inhibition Maintenance After Initial Chemoimmunotherapy in Patients with Extensive-Stage Small Cell Lung Cancer Adult CIRB - Early Phase Emphasis
10630 ETCTN Phase 1 Trial of Iadademstat in Combination with Venetoclax and Azacitidine in Patients with Treatment Naive AML Adult CIRB - Early Phase Emphasis
10636 ETCTN Phase 1 Trial of CA-4948 in Combination with Pembrolizumab to Overcome Resistance to PD-1/PD-L1 Blockade in Metastatic Urothelial Cancer Adult CIRB - Early Phase Emphasis
10637 ETCTN A Phase 2 Study of Venetoclax in Relapsed Classic or Variant Hairy Cell Leukemia Adult CIRB - Early Phase Emphasis