CIRB Studies
Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
| Study Number | Lead Group | Study Title | CIRB | Study Status |
|---|---|---|---|---|
| EA6134 | ECOG-ACRIN | DREAMseq (Doublet, Randomized Evaluation in Advanced Melanoma Sequencing) A Phase III Trial | Adult CIRB - Late Phase Emphasis | Available to Open |
| NWU20-02-01 | CLO-Northwestern University | Surgical Window of Opportunity Study of Megestrol Acetate Compared with Megestrol Acetate and Metformin for Endometrial Intraepithelial Neoplasia | Cancer Prevention and Control CIRB | Available to Open |
| EA2165 | ECOG-ACRIN | A Randomized Phase II Study of Nivolumab After Combined Modality Therapy (CMT) in High Risk Anal Cancer | Adult CIRB - Late Phase Emphasis | Available to Open |
| CCTG-HN11 | NCIC CTG | SPECT-CT Guided Elective Contralateral Neck Treatment (Select) for Patients with Lateralized Oropharyngeal Cancer: A Phase III Randomized Controlled Trial | Adult CIRB - Late Phase Emphasis | Available to Open |
| 10096 | ETCTN | A Phase 1/2 Study of Combination Olaparib and Radium-223 in Men with Metastatic Castration-Resistant Prostate Cancer with Bone Metastases (COMRADE) | Adult CIRB - Early Phase Emphasis | Available to Open |
| EA2222 | ECOG-ACRIN | A Randomized Phase III Study of Systemic Therapy with or without Hepatic Arterial Infusion for Unresectable Colorectal Liver Metastases: The PUMP Trial | Adult CIRB - Late Phase Emphasis | Available to Open |
| EAZ171 | ECOG-ACRIN | Prospective validation trial of taxane therapy (docetaxel or weekly paclitaxel) and risk of chemotherapy-induced peripheral neuropathy in African American women | Cancer Prevention and Control CIRB | Available to Open |
| ARAR2221 | COG | Phase 2 Study Using Chemoimmunotherapy with Gemcitabine, Cisplatin and Nivolumab in Newly Diagnosed Nasopharyngeal Carcinoma (NPC) | Pediatric CIRB | Available to Open |
| 10287 | ETCTN | A randomized Phase I/II trial of fulvestrant and abemaciclib in combination with copanlisib (FAC) versus fulvestrant and abemaciclib alone (FA) for endocrine-resistant, hormone receptor positive, HER2 negative metastatic breast cancer (FAC vs FA) | Adult CIRB - Early Phase Emphasis | Available to Open |
| N107C | NCCTG | A Phase III Trial of Post-Surgical Stereotactic Radiosurgery (SRS) Compared with Whole Brain Radiotherapy (WBRT) for Resected Metastatic Brain Disease | Adult CIRB - Late Phase Emphasis | Available to Open |