CIRB Studies
Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
| Study Number | Lead Group | Study Title | CIRB | Study Status |
|---|---|---|---|---|
| PED-CITN-01 | Pediatric CITN | 3CI Study: Childhood Cancer Combination Immunotherapy. Phase 1b and Expansion Study of Nivolumab Combination Immunotherapy in Children, Adolescent and Young Adult (CAYA) Patients with Relapsed/Refractory Hypermutant Cancers | Pediatric CIRB | Completed |
| PEPN21EHR/PBTC-N15 | Pediatric CITN | Pilot Study to Enable Electronic Laboratory Data Transfer into Medidata Rave | Pediatric CIRB | Completed |
| PED-CITN-03 | Pediatric CITN | Phase 1 Trial of Hu5F9-G4 (Magrolimab) Combined with Dinutuximab in Children and Young Adults with Relapsed and Refractory Neuroblastoma or Relapsed Osteosarcoma | Pediatric CIRB | Available to Open |
| CITN-17 | CITN | Phase 1 Study of NT-I7 (rhIL-7-hyFc) for the Treatment of Kaposi Sarcoma in Patients With or Without Infection with HIV | Adult CIRB - Early Phase Emphasis | Available to Open |
| CITN-14 | CITN | A Randomized Phase II Study of Atezolizumab (MPDL3280A) plus Recombinant Human IL-7 (CYT107) in patients with locally advanced or metastatic urothelial carcinoma | Adult CIRB - Early Phase Emphasis | Available to Open |
| ABTC-1701 | ABTC | Pilot Surgical PK Study of BGB324 in Recurrent Glioblastoma Patients | Adult CIRB - Early Phase Emphasis | Available to Open |
| ABTC-1802 | ABTC | A Phase II Study of Binimetinib in Combination with Encorafenib in Adults with Recurrent BRAF V600-Mutated High-Grade Astrocytoma or other Primary Brain Tumor | Adult CIRB - Late Phase Emphasis | Available to Open |
| ABTC-1801 | ABTC | Phase I/II Study of Pamiparib (BGB-290) with Temozolomide in Recurrent Gliomas with IDH1/2 Mutations | Adult CIRB - Early Phase Emphasis | Available to Open |
| ABTC-1804 | ABTC | Determining the Dose of Regadenoson Most Likely to Transiently Alter the Integrity of the Blood-Brain Barrier in Patients with Gliomas | Adult CIRB - Late Phase Emphasis | Available to Open |
| PBTC-051 | PBTC | Phase I Study to Evaluate the Safety and Tolerability of the CD40 Agonistic Monoclonal Antibody APX005M in Pediatric Subjects with Recurrent/Refractory Brain Tumors and Newly Diagnosed Brain Stem Glioma | Pediatric CIRB | Available to Open |