CIRB Studies
Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
| Study Number | Lead Group | Study Title | CIRB | Study Status |
|---|---|---|---|---|
| S2013 | SWOG | Immune Checkpoint Inhibitor Toxicity (I-CHECKIT): A Prospective Observational Study | Cancer Prevention and Control CIRB | Available to Open |
| S2015 | SWOG | Melanoma Margins Trial (MelMarT): A Phase III, Multi-Centre, Multi-National Randomised Control Trial Investigating 1cm v 2cm Wide Excision Margins for Primary Cutaneous Melanoma | Adult CIRB - Late Phase Emphasis | Available to Open |
| S0232 | SWOG | Double-Blinded Placebo Controlled Phase III Trial Comparing Dexamethasone (DEX) to the Combination of DEX + CC-5013 in Patients with Previously Untreated Multiple Myeloma who are Not Immediately Undergoing Autologous Stem Cell Transplant | Adult CIRB - Late Phase Emphasis | Completed |
| S1607 | SWOG | A Phase II Study of Combining Talimogene Laherparepvec (T-VEC) (NSC-785349) and MK-3475 (Pembrolizumab) (NSC-776864) in Patients with Advanced Melanoma who have Progressed on ANTI-PD1/L1 Based Therapy | Adult CIRB - Late Phase Emphasis | Available to Open |
| S1900G | SWOG | A Randomized Phase II Study of INC280 (capmatinib) plus Osimertinib with or without Ramucirumab in Participants with EGFR-Mutant, MET-Amplified Stage IV or Recurrent Non-Small Cell Lung Cancer (Lung-MAP Sub-Study) | Adult CIRB - Late Phase Emphasis | Available to Open |
| MAY2016-07-01F | CP-CTNet_CLO-Mayo Clinic | Review of Post-Study Clinical Endoscopy Reports in Follow Up to MAY2016-07-01 Weekly Erlotinib for Familial Adenomatous Polyposis | Cancer Prevention and Control CIRB | Completed |
| MAY2016-07-01 | CP-CTNet_CLO-Mayo Clinic | Phase II Trial of Weekly Erlotinib Dosing to Reduce Duodenal Polyp Burden Associated with Familial Adenomatous Polyposis | Cancer Prevention and Control CIRB | Completed |
| MAY2015-05-01 | CP-CTNet_CLO-Mayo Clinic | Randomized, double-blind, placebo-controlled trial of Meriva® (curcuminoids) as a candidate chemoprevention agent for gastric carcinogenesis | Cancer Prevention and Control CIRB | Available to Open |
| MAY2016-08-01 | CP-CTNet_CLO-Mayo Clinic | A Pilot Study of MUC1 Vaccine in Current and Former Smokers at High Risk for Lung Cancer | Cancer Prevention and Control CIRB | Available to Open |
| MAY2017-09-01 | CP-CTNet_CLO-Mayo Clinic | Phase I Double-Blind, Placebo-Controlled Trial of 27 mg Dolcanatide (SP-333) to Demonstrate Colorectal Bioactivity in Healthy Volunteers | Cancer Prevention and Control CIRB | Completed |