CIRB Studies
Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
| Study Number | Lead Group | Study Title | CIRB | Study Status |
|---|---|---|---|---|
| EA1151 | ECOG-ACRIN | Tomosynthesis Mammographic Imaging Screening Trial (TMIST) | Cancer Prevention and Control CIRB | Available to Open |
| 10509 | ETCTN | A Phase 1 Study of BET Bromodomain Inhibitor ZEN003694 in Combination with the CDK4/6 Inhibitor Abemaciclib in Patients with NUT Carcinoma and Other Solid Tumors | Adult CIRB - Early Phase Emphasis | Available to Open |
| NRG-BN012 | NRG | A Randomized Phase III Trial of Pre-Operative Compared to Post-Operative Stereotactic Radiosurgery in Patients with Resectable Brain Metastases | Adult CIRB - Late Phase Emphasis | Available to Open |
| ADVL1514 | COG | A Phase 1 Study of ABI-009 (nab-Rapamycin) (IND# 133537) in Pediatric Patients with Recurrent or Refractory Solid Tumors, Including CNS Tumors as a Single Agent and in Combination with Temozolomide and Irinotecan | Pediatric CIRB | Available to Open |
| A171601 | Alliance | A phase II trial assessing the tolerability of palbociclib in combination with letrozole or fulvestrant in patients aged 70 and older with estrogen receptor-positive, HER2-negative metastatic breast cancer | Cancer Prevention and Control CIRB | Available to Open |
| EA8211 | ECOG-ACRIN | Phase III Randomized Trial of Stereotactic Ablative Radiotherapy (SAbR) for Oligometastatic Advanced Renal Carcinoma (SOAR) | Adult CIRB - Late Phase Emphasis | Available to Open |
| A062102 | Alliance | Randomized Phase 2 Study of Iberdomide Maintenance Therapy Following Idecabtagene Vicleucel CAR-T in Multiple Myeloma Patients | Adult CIRB - Late Phase Emphasis | Available to Open |
| 10302 | ETCTN | Phase II Trial of Radium-223 Dichloride in Combination with Paclitaxel in Patients with Bone Metastatic Breast Cancer | Adult CIRB - Early Phase Emphasis | Available to Open |
| A151804 | Alliance | Establishment of a National Biorepository to Advance Studies of Immune-Related Adverse Events | Adult CIRB - Late Phase Emphasis | Available to Open |
| NRG-GY003 | NRG | Phase II Randomized Trial of Nivolumab with or without Ipilimumab in Patients with Persistent or Recurrent Epithelial Ovarian; Primary Peritoneal or Fallopian Tube Cancer | Adult CIRB - Early Phase Emphasis | Available to Open |