CIRB Studies
Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
| Study Number | Lead Group | Study Title | CIRB | Study Status |
|---|---|---|---|---|
| RTOG-0126 | RTOG | A Phase III Randomized Study of High Dose 3D-CRT/IMRT versus Standard Dose 3D-CRT/IMRT in Patients Treated for Localized Prostate Cancer | Adult CIRB - Late Phase Emphasis | Completed |
| NSABP-B-36 | NSABP | A Clinical Trial of Adjuvant Therapy Comparing Six Cycles of 5-Fluorouracil; Epirubicin and Cyclophosphamide (FEC) to Four Cycles of Adriamycin and Cyclophosphamide (AC) in Patients with Node-Negative Breast Cancer | Adult CIRB - Late Phase Emphasis | Completed |
| CALGB-49808 | CALGB | A 2 X 2 X 2 Factorial Randomized Phase III Trial of Multimodality Therapy Comparing 4 Cycles of Doxorubicin and Cyclophosphamide with or without Dexrazoxane (AC +/- Z) Followed by 12 Weeks of Weekly Paclitaxel with or without Trastuzumab (T H) Followed by Local Therapy Followed by 40 Weeks of Weekly Trastuzumab or none in Women with HER-2+ STAGE IIIA; IIIB or Regional Stage IV Breast Cancer **ADMINISTRATIVELY COMPLETED as of December 15; 2002** | Adult CIRB - Late Phase Emphasis | Completed |
| AAML05P1 | COG | Killer Immunoglobulin-like Receptor (KIR) Incompatible Unrelated Donor Hematopoietic Stem Cell Transplantation (SCT) for AML with Monosomy 7; -5/5q-; High FLT3-ITD AR; or Refractory and Relapsed Acute Myelogenous Leukemia (AML) in Children: A Children's Oncology Group (COG) Study (A Groupwide Pilot Study) | Pediatric CIRB | Completed |
| MDA2014-04-02 | CP-CTNet_CLO-MD Anderson | VADIS Trial: Phase II trial of Nelipepimut-S Peptide Vaccine in Women with DCIS of the Breast | Cancer Prevention and Control CIRB | Completed |
| ADVL0221 | COG | A Phase II Study of Trabectedin (ET-743; Yondelis) in Children with Recurrent Rhabdomyosarcoma; Ewing Sarcoma; or Nonrhabdomyosarcomatous Soft Tissue Sarcomas | Pediatric CIRB | Completed |
| E4A08 | ECOG | A Randomized Phase III Trial of Melphalan and Dexamethasone (MDex) versus Bortezomib; Melphalan; and Dexamethasone (BMDex) for Untreated Patients with Systemic Light-chain (AL) Amyloidosis Ineligible for Autologous Stem-cell Transplantation | Adult CIRB - Late Phase Emphasis | Completed |
| S0502 | SWOG | A Phase III Randomized Study of Imatinib; with or without Bevacizumab (NSC-704865); in Patients with Metastatic or Unresectable Gastrointestinal Stromal Tumors NCT #00324987 | Adult CIRB - Late Phase Emphasis | Completed |
| E2212 | ECOG | A Randomized; Double-Blinded; Placebo-Controlled Phase II Study of Adjuvant Everolimus Following the Resection of Metastatic Pancreatic Neuroendocrine Tumors to the Liver | Adult CIRB - Early Phase Emphasis | Completed |
| PEPN21EHR/PBTC-N15 | Pediatric CITN | Pilot Study to Enable Electronic Laboratory Data Transfer into Medidata Rave | Pediatric CIRB | Completed |