Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
|Study Number||Lead Group||Study Title||CIRB||Study Status|
|S1925||SWOG||Randomized, Phase II Study of Early Intervention with Venetoclax and Obinutuzumab versus Delayed Therapy with Venetoclax and Obinutuzumab in Newly Diagnosed Asymptomatic High-Risk Patients with Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL): EVOLVE CLL/SLL Study||Adult CIRB - Late Phase Emphasis||Available to Open|
|S1929||SWOG||Phase II Randomized Study of Maintenance Atezolizumab Versus Atezolizumab in Combination with Talazoparib in Patients with SLFN11 Positive Extensive Stage Small Cell Lung Cancer (ES-SCLC)||Adult CIRB - Late Phase Emphasis||Available to Open|
|S1931||SWOG||Phase III Trial Of Immunotherapy-Based Combination Therapy With Or Without Cytoreductive Nephrectomy For Metastatic Renal Cell Carcinoma (Probe Trial)||Adult CIRB - Late Phase Emphasis||Available to Open|
|S1933||SWOG||A Pilot Study of Hypofractionated Radiotherapy Followed by Atezolizumab Consolidation in Stage II or III NSCLC Patients with Borderline Performance Status||Adult CIRB - Late Phase Emphasis||Available to Open|
|S2000||SWOG||A Randomized Phase 2 Trial of Encorafenib + Binimetinib + Nivolumab vs Ipilimumab + Nivolumab in BRAF-V600 Mutant Melanoma with Brain Metastases||Adult CIRB - Late Phase Emphasis||Available to Open|
|S2007||SWOG||A Phase II Trial of Sacituzumab Govitecan (IMMU-132) (NSC #820016) for Patients with HER2-Negative Breast Cancer and Brain Metastases||Adult CIRB - Late Phase Emphasis||Available to Open|
|S9910||SWOG||Leukemia Centralized Reference Laboratories and Tissue Repositories Ancillary||Adult CIRB - Late Phase Emphasis||Completed|
|S9925||SWOG||Lung Cancer Specimen Repository Protocol Ancillary||Adult CIRB - Late Phase Emphasis||Completed|
|SCUSF-0901||COG||SCUSF 0901 [ACCL0922] A Phase II Placebo-Controlled Trial of Modafinil to Improve Neurocognitive Deficits in Children Treated for a Primary Brain Tumor||Pediatric CIRB||Available to Open|
|SWOG-9007||SWOG||Cytogenetic Studies in Leukemia Patients||Adult CIRB - Late Phase Emphasis||Completed|