CIRB Studies

Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.

To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.

Displaying 1 - 10 of 730
Study Number Lead Group Study Title CIRB Study Status
ACOSOG-Z1041 ACSOG A Randomized Phase III Trial Comparing a Neoadjuvant Regimen of FEC-75 Followed by Paclitaxel Plus Trastuzumab With a Neoadjuvant Regimen of Paclitaxel Plus Trastuzumab Followed by FEC-75 Plus Trastuzumab in Patients with HER-2 Positive Operable Breast Cancer Adult CIRB - Late Phase Emphasis Available to Open
ACOSOG-Z4032 ACSOG A Randomized Phase III Study of Sublobar Resection versus Sublobar Resection Plus Brachytherapy in High Risk Patients with Non-Small Cell Lung Cancer (NSCLC); 3 cm or Smaller Adult CIRB - Late Phase Emphasis Available to Open
ACOSOG-Z4099 ACSOG A Randomized Phase III Study of Sublobar Resection (+/- Brachytherapy) versus Stereotactic Body Radiation Therapy in High Risk Patients with Stage I Non-Small Cell Lung Cancer (NSCLC)<br><br> Adult CIRB - Late Phase Emphasis Completed
ACOSOG-Z6051 ACSOG A Phase III Prospective Randomized Trial Comparing Laparoscopic-assisted Resection Versus Open Resection for Rectal Cancer Adult CIRB - Late Phase Emphasis Available to Open
ACOSOG-Z9031 ACSOG A Phase III Randomized Study of Preoperative Radiation Plus Surgery Versus Surgery Alone for Patients with Retroperitoneal Sarcomas (RPS) Adult CIRB - Late Phase Emphasis Completed
ACOSOG-Z1031 ACSOG A Randomized Phase III Trial Comparing 16 to 18 Weeks of Neoadjuvant Exemestane (25 mg daily); Letrozole (2.5 mg); or Anastrozole (1 mg) in Postmenopausal Women with Clinical Stage II and III Estrogen Receptor Positive Breast Cancer Adult CIRB - Late Phase Emphasis Available to Open
A221505 Alliance Phase III Randomized Trial of Hypofractionated Post Mastectomy Radiation with Breast Reconstruction Cancer Prevention and Control CIRB Available to Open
A031704 Alliance PD-Inhibitor (Nivolumab) and Ipilimumab Followed by Nivolumab vs. VEGF TKI Cabozantinib with Nivolumab: A Phase III Trial in Metastatic Untreated Renal Cell Cancer [PDIGREE] Adult CIRB - Late Phase Emphasis Available to Open
A091304 Alliance A Phase I /Randomized Phase II Study of MLN0128 vs. Pazopanib In Patients With Locally Advanced/Unresectable And/Or Metastatic Sarcoma Adult CIRB - Early Phase Emphasis Available to Open
A041702 Alliance A Randomized Phase III Study of Ibrutinib Plus Obinutuzumab Versus Ibrutinib plus Venetoclax and Obinutuzumab in Untreated Older Patients (= 70 Years of Age) with Chronic Lymphocytic Leukemia (CLL) Adult CIRB - Late Phase Emphasis Available to Open
Displaying 1 - 10 of 730