CIRB Studies
Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
| Study Number | Lead Group | Study Title | CIRB | Study Status |
|---|---|---|---|---|
| ACNS1022 | COG | A Phase II Randomized Trial of Lenalidomide (NSC # 703813; IND # 70116) in Pediatric Patients with Recurrent; Refractory or Progressive Juvenile Pilocytic Astrocytomas and Optic Pathway Gliomas: A Groupwide Phase II Study | Pediatric CIRB | Available to Open |
| NRG-CC011 | NRG | Cognitive Training for Cancer Related Cognitive Impairment in Breast Cancer Survivors: A Multi-Center Randomized Double-Blinded Controlled Trial | Cancer Prevention and Control CIRB | Available to Open |
| DCP-001 | NCI | Use of a Clinical Trial Screening Tool to Address Cancer Health Disparities in the NCI Community Oncology Research Program (NCORP) | Cancer Prevention and Control CIRB | Available to Open |
| CALGB-10603 | CALGB | A Phase III Randomized; Double-Blind Study of Induction (Daunorubicin/Cytarabine) and Consolidation (High-Dose Cytarabine) Chemotherapy + Midostaurin (PKC412) (IND #101261) or Placebo in Newly Diagnosed Patients < 60 Years of Age with FLT3 Mutated Acute Myeloid Leukemia (AML) | Adult CIRB - Late Phase Emphasis | Available to Open |
| EA2176 | ECOG-ACRIN | A Randomized Phase III Study of Immune Checkpoint Inhibition with Chemotherapy in Treatment-Naïve Metastatic Anal Cancer Patients | Adult CIRB - Late Phase Emphasis | Available to Open |
| 10402 | ETCTN | BAY 1895344 Plus Topoisomerase-1 (Top1) Inhibitors in Patients with Advanced Solid Tumors, Phase I Studies with Expansion Cohorts in Small Cell Lung Carcinoma (SCLC), Poorly Differentiated Neuroendocrine Carcinoma (PD-NEC) and Pancreatic Adenocarcinoma (PDA) | Adult CIRB - Early Phase Emphasis | Available to Open |
| 10009 | ETCTN | A Phase 1b study of the anti-PD1 antibody Pembrolizumab in combination with the histone deacetylase inhibitor; Entinostat for treatment of patients with myelodysplastic syndromes after DNA methyltransferase inhibitor therapy failure | Adult CIRB - Early Phase Emphasis | Available to Open |
| 10434 | ETCTN | Randomized Phase 2 Study of CPX-351 + Pomalidomide versus CPX-351 in Newly Diagnosed AML with MDS-Related Changes | Adult CIRB - Early Phase Emphasis | Available to Open |
| URCC-16092 | NCORP-University of Rochester Cancer Center | Phase II Study of Low-Dose Ibuprofen for Cognitive Problems in Patients with Cancer | Cancer Prevention and Control CIRB | Available to Open |
| NWU20-04-01 | CLO-Northwestern University | Metformin for Chemoprevention of Lung Cancer in High-Risk Overweight or Obese Individuals | Cancer Prevention and Control CIRB | Available to Open |