CIRB Studies
Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
| Study Number | Lead Group | Study Title | CIRB | Study Status |
|---|---|---|---|---|
| EA2212 | ECOG-ACRIN | A Randomized Phase II Study of Perioperative Atezolizumab +/- Chemotherapy in Resectable MSI-H/dMMR Gastric and Gastroesophageal Junction (GEJ) Cancer | Adult CIRB - Early Phase Emphasis | Available to Open |
| ANBL2131 | COG | A Phase 3 Study of Dinutuximab Added to Intensive Multimodal Therapy for Children with Newly Diagnosed High-Risk Neuroblastoma | Cancer Prevention and Control CIRB | Available to Open |
| A011502 | Alliance | A Randomized Phase III Double Blinded Placebo-Controlled Trial of Aspirin as Adjuvant Therapy for HER2 Negative Breast Cancer: The ABC Trial | Adult CIRB - Late Phase Emphasis | Available to Open |
| A031702 | Alliance | A Phase II Study of Ipilimumab, Cabozantinib, and NIvolumab in Rare Genitourinary Cancers (ICONIC) | Adult CIRB - Late Phase Emphasis | Available to Open |
| RTOG-1016 | RTOG | Phase III Trial of Radiotherapy Plus Cetuximab Versus Chemoradiotherapy in HPV-Associated Oropharynx Cancer | Adult CIRB - Late Phase Emphasis | Available to Open |
| E1208 | ECOG | A Phase III Randomized; Double-Blind Trial of Chemoembolization with or without Sorafenib in Unresectable Hepatocellular Carcinoma (HCC) in Patients with and without Vascular Invasion | Adult CIRB - Late Phase Emphasis | Available to Open |
| AEWS07B1 | COG | A COG Study for Collecting and Banking Ewing Sarcoma Specimens | Pediatric CIRB | Available to Open |
| EA2131 | ECOG-ACRIN | A Phase I and Randomized Phase II Study of Nab-Paclitaxel/Gemcitabine with or without AZD1775 for Treatment of Metastatic Adenocarcinoma of the Pancreas | Adult CIRB - Early Phase Emphasis | Available to Open |
| 10231 | NCORP-National Institutes of Health | NCORP Tissue Procurement Protocol: An NCI Cancer Moonshot Study | Adult CIRB - Late Phase Emphasis | Available to Open |
| PEPN1812 | PEP-CTN | A Phase 1 Trial of the CD123 X CD3 DART® Molecule Flotetuzumab (NSC#808294, IND#145986) in Children, Adolescents, and Young Adults with Relapsed or Refractory Acute Myeloid Leukemia | Pediatric CIRB | Available to Open |