CIRB Studies
Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
| Study Number | Lead Group | Study Title | CIRB | Study Status |
|---|---|---|---|---|
| A082101 | Alliance | Multimodality Therapy with Immunotherapy in Stage I-IIIA Sarcomatoid Mesothelioma | Adult CIRB - Late Phase Emphasis | Available to Open |
| S1900E | SWOG | A Phase II Study of AMG 510 in Participants with Previously Treated Stage IV or Recurrent KRAS G12C Mutated Non-Squamous Non-Small Cell Lung Cancer (ECOG-ACRIN LungMAP Sub-Study) | Adult CIRB - Late Phase Emphasis | Available to Open |
| 10603 | ETCTN | A Phase 2 Study of M1774 in Refractory SPOP-mutant Prostate Cancer | Adult CIRB - Early Phase Emphasis | Available to Open |
| AAML08B1 | COG | Biology Study of Transient Myeloproliferative Disorder (TMD) in Children with Down Syndrome (DS) | Pediatric CIRB | Available to Open |
| A011502 | Alliance | A Randomized Phase III Double Blinded Placebo-Controlled Trial of Aspirin as Adjuvant Therapy for HER2 Negative Breast Cancer: The ABC Trial | Adult CIRB - Late Phase Emphasis | Available to Open |
| AGCT1532 | COG | Phase 3 Accelerated BEP Trial: A randomized phase 3 trial of accelerated versus standard BEP chemotherapy for patients with intermediate and poor-risk metastatic germ cell tumors | Pediatric CIRB | Available to Open |
| NRG-GY007 | NRG | A Phase I/II Study of Ruxolitinib with Front-Line Neoadjuvant and Post-Surgical Therapy in Patients with Advanced Epithelial Ovarian; Fallopian Tube; or Primary Peritoneal Cancer | Adult CIRB - Late Phase Emphasis | Available to Open |
| AREN03B2 | COG | Renal Tumors Classification; Biology; and Banking Study | Pediatric CIRB | Available to Open |
| S1007 | SWOG | A Phase III; Randomized Clinical Trial of Standard Adjuvant Endocrine Therapy +/- Chemotherapy in Patients with 1-3 Positive Nodes; Hormone Receptor-Positive and HER2-Negative Breast Cancer with Recurrence Score (RS) of 25 or Less. RxPONDER: A Clinical Trial RX for Positive Node; Endocrine Responsive Breast Cancer | Adult CIRB - Late Phase Emphasis | Available to Open |
| E1208 | ECOG | A Phase III Randomized; Double-Blind Trial of Chemoembolization with or without Sorafenib in Unresectable Hepatocellular Carcinoma (HCC) in Patients with and without Vascular Invasion | Adult CIRB - Late Phase Emphasis | Available to Open |