• Virtually no advance preparation for IRB review at your site - just download a complete IRB packet

• No more waiting for the next meeting of the full IRB

• Enroll patients faster

CIRB BENEFITS TO LOCAL IRBs

• Carry out local review without convening the full board

• Eliminate preparations for full Board review of CIRB approved studies

• Continuing review, amendments, and adverse events are handled by the CIRB (local adverse events remain under local as well as central review)

CURRENT STATUS OF THE CIRBs

The Adult CIRB has been meeting twice monthly and reviewing clinical trials since January 2001. The Adult Board currently reviews all Phase 3 Cooperative Group trials from the ACOSOG, CALGB, ECOG, GOG, NCCTG, NCIC, NSABP, RTOG, and SWOG, as well as any other studies opened in the Cancer Trials Support Unit (CTSU).

The Pediatric CIRB was constituted in June 2004 and began meeting in November 2004. It reviews all NCI-approved COG Phase 2, 3, and Pilot protocols.

Both Boards are composed of individuals who represent a broad range of oncology scientific and nonscientific disciplines.  These may include oncology physicians, nurses, patient representatives, pharmacists, ethicists and attorneys.  None of the members, or the Chairs, are NCI employees.

If you have any questions, concerns, or a serious interest in joining please visit the Contact page for CIRB contact information.